Endocrinology

This systematic review evaluates the efficacy and safety of semaglutide 2.4 mg for weight management in adults with obesity, synthesizing evidence from the STEP clinical trial program.

This network meta-analysis compares tirzepatide with available GLP-1 receptor agonists for glycemic control and weight reduction in adults with type 2 diabetes across 42 randomized trials.

This multicenter randomized trial evaluates the effect of levothyroxine replacement therapy on quality of life, cardiovascular events, and cognitive function in adults aged 65 years and older with subclinical hypothyroidism.